HUMAN HYALURONIC ACID

📋 Quick facts

Quick Facts:

• Category: other
• Also Known As: ヒトヒアルロン酸

Proven Benefits At A Glance:

• Hyaluronic acid (HA) is a natural molecule your body produces through three different enzymes called HAS1, HAS2, and HAS3
• HA exists both outside cells (in the spaces between them) and inside cells
• The sources provided focus on HA’s role in cancer biology, not skincare benefits
• No skincare, anti-aging, or cosmetic benefits are documented in the available research

📊 Comedogenicity

🛡️ Safety rating

Safety tier is a starting heuristic from regulatory status and comedogenic rating, not a dermatological verdict — see our Terms for the full disclaimer. Research confidence reflects how many real cited studies back this ingredient, not the strength of their findings.

🌍 Regulatory Status

💧 Skin Type Compatibility

⚠️ Don’t Combine With

📚 Research & Evidence

🔬 The Science

The term ‘human hyaluronic acid’ refers to HA molecules that your body synthesizes naturally using three membrane-spanning enzymes (Cell Commun Signal, 2017). These enzymes—HAS1, HAS2, and HAS3—produce HA in different locations within and around cells. HAS1 is notably localized in the cytoplasmic space, where it makes intracellular HA (meaning HA inside the cell itself), while the other two enzymes produce HA in the extracellular matrix—the structural material between your cells. HA is classified as a glycosaminoglycan, which is simply a type of large sugar-based molecule found throughout your body. The research abstracts provided focus exclusively on HA’s involvement in cancer cell biology.

Specifically, they document how overexpression of the HAS1 enzyme correlates with tumor progression, genetic instability, and cancer cell characteristics (Cell Commun Signal, 2017). The sources do not contain any information about HA’s effects on skin hydration, wrinkles, elasticity, wound healing, or any other cosmetic or skincare outcome. To make evidence-based claims about ‘human hyaluronic acid’ in skincare, you would need different research sources that specifically study topical or injectable HA in dermatological or cosmetic contexts.

📄 Related Research

Matched by search — not necessarily verified support for every statement above.

• Nguyen N et al. (2017). Human hyaluronic acid synthase-1 promotes malignant transformation via epithelial-to-mesenchymal transition, micronucleation and centrosome abnormalities. Cell Commun Signal.

🧴 Products Containing HUMAN HYALURONIC ACID