LOW SODIUM

📋 Quick facts

Quick Facts:

• Category: other
• Also Known As: Con poco sodio, Alacsony nátriumtartalmú, Baix en sodi, Faible teneur en sodium, โซเดียมต่ำ, Baixo teor de sódio, Natriumarm, דל נתרן, Bajo en sodio, Low sodium, Низкое содержание натрия, Vähänatriuminen, Hyponatremia, low sodium, vähänatriuminen

Proven Benefits At A Glance:

• Low sodium dialysate was tested in kidney dialysis patients to see if it could reduce sodium buildup in skin and muscle tissue
• In adjusted analysis, low sodium dialysate was linked to decreased skin sodium, but the effect on muscle sodium wasn’t clear
• The study involved 23 patients who completed both high-sodium and low-sodium treatment periods
• No serious safety concerns were found with low-sodium dialysate treatment
• Ultrafiltration rate (how much fluid is removed during dialysis) appeared to have a stronger effect on reducing tissue sodium than dialysate sodium alone

📊 Comedogenicity

🛡️ Safety rating

Safety tier is a starting heuristic from regulatory status and comedogenic rating, not a dermatological verdict — see our Terms for the full disclaimer. Research confidence reflects how many real cited studies back this ingredient, not the strength of their findings.

🌍 Regulatory Status

💧 Skin Type Compatibility

⚠️ Don’t Combine With

📚 Research & Evidence

🔬 The Science

This research comes from a randomized crossover trial published in Kidney International Reports, where dialysis patients were exposed to both standard dialysate (containing 138 mEq/l sodium) and low-sodium dialysate (132 mEq/l sodium) for 4-week periods each. Tissue sodium was measured using 23Na magnetic resonance imaging, a specialized imaging technique that can specifically detect sodium in tissues rather than just measuring it in blood. #1: When researchers adjusted their analysis for each patient’s starting sodium levels and how much fluid was removed during their dialysis sessions, low-sodium dialysate showed an association with decreased skin sodium (Kidney Int Rep, 2026). #2: However, the same adjusted analysis did not show a clear connection between low-sodium dialysate and reduced muscle sodium accumulation (Kidney Int Rep, 2026).

Notably, #3: the study found that ultrafiltration rate—the amount of fluid removed during each dialysis session—was significantly associated with reducing both skin and muscle sodium, suggesting this dialysis parameter may be more influential than sodium concentration alone (Kidney Int Rep, 2026). The researchers also measured inflammation using high-sensitivity C-reactive protein (hs-CRP) and a protein marker called prealbumin, but found no significant changes between the two treatment types (Kidney Int Rep, 2026). The authors acknowledge their findings are limited and call for larger future studies to understand how low-sodium dialysate and ultrafiltration rates work together and what their real clinical impact might be.

📄 Related Research

Matched by search — not necessarily verified support for every statement above.

• Ertuglu LA et al. (2026). Randomized Crossover Trial of Low Sodium Dialysate on Tissue Sodium Accumulation in Hemodialysis. Kidney Int Rep.

🧴 Products Containing LOW SODIUM