SCUTELLARIA BARBATA EXTRACT

📋 Quick facts

Quick Facts:

• Category: other
• Also Known As: 半枝莲（SCUTELLARIA BARBATA）提取物

Proven Benefits At A Glance:

• Scutellaria barbata is a traditional Chinese herb historically used as an anti-inflammatory and diuretic
• Research shows the extract has inhibitory effects on multiple cancer cell types including lung, digestive, liver, and breast cancers
• The extract demonstrated antibacterial activity, particularly against Pseudomonas aeruginosa
• In lab studies, the extract killed lung cancer cells through apoptosis (programmed cell death) and cytotoxic effects
• Most research to date has been conducted in laboratory settings, not in humans

📊 Comedogenicity

🛡️ Safety rating

Safety tier is a starting heuristic from regulatory status and comedogenic rating, not a dermatological verdict — see our Terms for the full disclaimer. Research confidence reflects how many real cited studies back this ingredient, not the strength of their findings.

🌍 Regulatory Status

💧 Skin Type Compatibility

⚠️ Don’t Combine With

📚 Research & Evidence

🔬 The Science

Scutellaria barbata extract has been studied for two main areas of potential benefit. #1: Cancer cell inhibition — when researchers tested ethanol extracts of Scutellaria barbata against human lung cancer cells in the lab, the extract significantly slowed cancer cell growth (Life Sci, 2004). The mechanism appears to involve triggering apoptosis (a type of programmed cell death) and direct cytotoxic effects on cancer cells. Gene analysis revealed that 16 genes involved in DNA damage, cell cycle control, and protein regulation were substantially altered by the extract, suggesting these pathways are involved in how the extract affects cancer cells (Life Sci, 2004).

Notably, one gene related to dendritic cell function (CD209) was dramatically downregulated, though the researchers noted that further studies are needed to understand what role this plays. #2: Antibacterial activity — in a more recent laboratory study using advanced nanotechnology, researchers encapsulated Scutellaria barbata extract in tiny lipid-based carriers to improve how the body absorbs and uses it (Bioprocess Biosyst Eng, 2024). When tested against the bacterium Pseudomonas aeruginosa, the encapsulated extract showed improved antimicrobial potency compared to the free extract alone, suggesting that the delivery method can enhance the extract’s natural antibacterial properties (Bioprocess Biosyst Eng, 2024). Important context: All of these findings come from laboratory and test-tube studies, not human clinical trials.

While traditional Chinese medicine has long used this plant for anti-inflammatory and diuretic purposes, the scientific research supporting these traditional uses is limited in the available abstracts. The cancer research is preliminary and focuses on understanding mechanism rather than clinical efficacy.

📄 Related Research

Matched by search — not necessarily verified support for every statement above.

• Jetti R et al. (2024). Ultrasonic synthesis of green lipid nanocarriers loaded with Scutellaria barbata extract: a sustainable approach for enhanced anticancer and antibacterial therapy. Bioprocess Biosyst Eng.
• Yin X et al. (2004). Anticancer activity and mechanism of Scutellaria barbata extract on human lung cancer cell line A549. Life Sci.

🧴 Products Containing SCUTELLARIA BARBATA EXTRACT