Mia Seilern
⚠️ Data is provided for informational purposes only. It may contain inaccuracies and should be independently verified. This is not medical advice. Consult a healthcare professional before making health decisions.

Description: PANAX GINSENG ROOT EXTRACT — antioxidant, revitalizing, circulation support (Ginseng).

All Functions: antioxidant, revitalizing, circulation support (Ginseng)

Quick Facts:

  • Category: active

Proven Benefits At A Glance:

  • Panax ginseng root extract contains phenolic acids, including vanillic acid, a compound studied for skin benefits
  • Research shows ginseng root extract may support skin’s natural antioxidant defenses like glutathione and superoxide dismutase
  • In cell studies, vanillic acid from ginseng suppressed melanin production by affecting specific signaling pathways
  • Animal studies suggest ginseng may have chemopreventive properties, though human evidence is limited
Safety: Generally Low ConcernResearch confidence: Fair

Safety tier is a starting heuristic from regulatory status and comedogenic rating, not a dermatological verdict — see our Terms for the full disclaimer. Research confidence reflects how many real cited studies back this ingredient, not the strength of their findings.

🧪 PANAX GINSENG ROOT EXTRACT

Chemical structure of PANAX GINSENG ROOT EXTRACT

PANAX GINSENG ROOT EXTRACT

CAS Number: 84650-12-4

Also Known As:

Category: active

EC Number: 283-493-7

Korean Name: 인삼추출물

Panax Ginseng Root Extract is an extract of the roots of the Ginseng, Panax ginseng, Araliaceae

PANAX GINSENG ROOT EXTRACT is an active ingredient used in skincare formulations.

antioxidantrevitalizingcirculation support (Ginseng)

🌍 Regulatory Status

EU: No restriction on fileUS: No restriction on file

📊 Comedogenicity

No data yet
Not rated for this ingredient yet.

📚 Research & Evidence

PUBMED CITATIONS
2
Data sources: EU CosIng PubMed

🔬 The Science

Panax ginseng root extract has been investigated for two main skincare-relevant properties based on available research. #1: Antioxidant support — According to research in the Journal of Ginseng Research, when ginseng root extract was given orally to mice exposed to carcinogenic chemicals, it significantly increased levels of protective molecules in both liver and skin tissue, including reduced glutathione, superoxide dismutase, catalase, and vitamin C. The same study found it also reduced lipid peroxidation (a marker of cellular damage). This suggests ginseng may support the skin’s own antioxidant defense system, though this animal research doesn’t directly translate to proven human skin benefits.

#2: Melanin regulation — Research published in Bioscience, Biotechnology, and Biochemistry identified vanillic acid as the most abundant phenolic acid in ginseng root extract. In laboratory cell studies, vanillic acid suppressed melanin production by inhibiting the NO/PKG signaling pathway and reducing tyrosinase activity (an enzyme involved in melanin synthesis). However, this was demonstrated in isolated cells, not in human skin, so real-world effectiveness remains unclear. Importantly, the animal cancer prevention study used oral doses and measured internal markers; it did not test topical application to skin. The melanin studies were conducted in cell cultures, not living tissue. Human clinical evidence specifically supporting these mechanisms in skincare products is not present in these sources.

💧 Skin Type Compatibility

No data yet
Per-skin-type data isn’t curated for this ingredient yet.

⚠️ Don’t Combine With

No data yet
No known incompatibilities on file for this ingredient.

🧴 Products Containing PANAX GINSENG ROOT EXTRACT

📄 Related Research

Matched by search — not necessarily verified support for every statement above.

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