ROSA CANINA EXTRACT

📋 Quick facts

Quick Facts:

• Category: other
• Also Known As: 狗牙蔷薇（ROSA CANINA）提取物

Proven Benefits At A Glance:

• Rosa canina extract is rich in phenolic compounds, particularly ascorbic acid and p-coumaric acid
• Research shows antioxidant and anti-inflammatory properties in laboratory and animal studies
• Studies have examined effects on cancer cells, diabetes markers, and muscle health — but mostly in cells or animals, not yet proven in humans
• Limited human clinical trials exist; most evidence comes from controlled lab and animal research

📊 Comedogenicity

🛡️ Safety rating

Safety tier is a starting heuristic from regulatory status and comedogenic rating, not a dermatological verdict — see our Terms for the full disclaimer. Research confidence reflects how many real cited studies back this ingredient, not the strength of their findings.

🌍 Regulatory Status

💧 Skin Type Compatibility

⚠️ Don’t Combine With

📚 Research & Evidence

🔬 The Science

Rosa canina extract has generated interest in phytomedicine research for multiple potential applications, though the evidence base remains primarily preclinical. Here’s what the current research shows: #1: Antioxidant composition — The extract contains measurable phenolic compounds (58.97 mg gallic acid equivalents per gram in one analysis), with ascorbic acid and p-coumaric acid identified as major components (Nutr Cancer, 2020). These phenolics are the compounds thought to drive antioxidant activity, though the research doesn’t yet specify which ones matter most for skin. #2: Cancer cell effects in the lab — In controlled cell culture studies, Rosa canina extract showed selective cytotoxic activity against human lung and prostate cancer cells while sparing normal fibroblast cells, working through mechanisms like cell cycle arrest and apoptosis (Nutr Cancer, 2020).

This is interesting foundational work, but these are early-stage findings in isolated cells, not evidence of cancer treatment in humans. #3: Blood sugar regulation in animal models — In diabetic rats, Rosa canina extract (especially spray-dried formulations) reduced blood glucose levels and altered the methylation patterns of genes involved in pancreatic beta-cell function and insulin production (Mol Biol Rep, 2024). Methylation is an epigenetic mechanism controlling gene activity, but again, this is animal research that has not been confirmed in human trials. #4: Muscle health and inflammation — In both cell cultures and mice with experimentally induced muscle atrophy, the extract reduced pro-inflammatory markers, boosted antioxidant enzymes, and preserved muscle mass and strength through pathways including PI3K/Akt/mTOR signaling (Nutrients, 2025).

The research suggests Rosa canina may help protect against muscle wasting driven by inflammation and oxidative stress. The sources are explicit that human clinical evidence is sparse; the research focuses on mechanistic studies to understand how the extract might work, not on proving it works in actual people using skincare products.

📄 Related Research

Matched by search — not necessarily verified support for every statement above.

• Kilinc K et al. (2020). Rosa canina Extract has Antiproliferative and Proapoptotic Effects on Human Lung and Prostate Cancer Cells. Nutr Cancer.
• Javid H et al. (2024). Rosa canina extract relieves methylation alterations of pancreatic genes in STZ-induced diabetic rats : Gene methylation in diabetic rats treated with an extract. Mol Biol Rep.
• Lee H et al. (2025). Rosa canina Extract Attenuates Muscle Atrophy in L6 Myotubes and Immobilized Mice. Nutrients.

🧴 Products Containing ROSA CANINA EXTRACT