VITIS VINIFERA (GRAPE) SEED

📋 Quick facts

Description: VITIS VINIFERA (GRAPE) SEED — CIR reviewed: safe as used in cosmetics. Report: Safety Assessment of Vitis vinifera-Grape-Derived Ingredients as Used in Cosmetics.

Quick Facts:

• Category: other
• Also Known As: 葡萄（VITIS VINIFERA）籽, 포도씨

Proven Benefits At A Glance:

• Grape seed extract contains compounds studied for antioxidant properties
• Research has focused on grape seed extract’s potential to counteract effects of the industrial chemical BPA
• Studies were conducted in rats and in human cell cultures, not human skin
• The research is preliminary and does not establish benefits for topical skincare use

📊 Comedogenicity

🛡️ Safety rating

Safety tier is a starting heuristic from regulatory status and comedogenic rating, not a dermatological verdict — see our Terms for the full disclaimer. Research confidence reflects how many real cited studies back this ingredient, not the strength of their findings.

🌍 Regulatory Status

💧 Skin Type Compatibility

⚠️ Don’t Combine With

📚 Research & Evidence

🔬 The Science

The available research on grape seed extract (a compound derived from Vitis vinifera grape seeds) centers on internal exposure to the industrial chemical bisphenol-A (BPA), not skincare applications. Here’s what the studies actually show: #1: In rat studies lasting 2 months, grape seed extract appeared to help restore some markers related to metabolic health that BPA had disrupted, including effects on insulin signaling and cholesterol regulation in the liver (Phytother Res, 2019). #2: In both rat studies and laboratory tests on human blood vessel cells, grape seed extract demonstrated antioxidant activity—meaning it appeared to reduce oxidative stress, a type of cellular damage—when BPA was introduced (Phytother Res, 2018 and 2019).

#3: In human cells grown in a dish, grape seed extract and related compounds showed protective effects against BPA-induced damage to vascular (blood vessel) cells, partly attributed to their antioxidant properties (Phytother Res, 2018). Important limitations: These studies involved either animal models or cells in controlled laboratory conditions, not human skin. The research addresses internal exposure to BPA, not topical skincare benefits. No studies in the provided sources examine grape seed extract applied to skin or its effects on skin aging, texture, or other cosmetic concerns. While the antioxidant properties documented in these studies are real, translating that to skincare efficacy would require separate human research on topical application.

📄 Related Research

Matched by search — not necessarily verified support for every statement above.

• Rameshrad M et al. (2019). Vitis vinifera (grape) seed extract and resveratrol alleviate bisphenol-A-induced metabolic syndrome: Biochemical and molecular evidences. Phytother Res.
• Rameshrad M et al. (2018). Bisphenol A vascular toxicity: Protective effect of Vitis vinifera (grape) seed extract and resveratrol. Phytother Res.

🧴 Products Containing VITIS VINIFERA (GRAPE) SEED

• ELEMIS Pro-Collagen Cleansing Balm
• EcoLove מרכך לשיער רגיל-יבש
• Santé Verte Nature & care permanent colour chocolate
• Caudalie Soin des lèvres
• Caudalie Vinoperfect crème mains anti taches
• Caudalie Soin corps nourrissant Thé des Vignes
• Caudalie Vinotherapist Crème réparatrice mains et ongles
• Palmolive Optims
• Burts Bees Baby Sunflower Lotion
• Les Cosmetiques Exfoliante corporal mineral mar muerto
• LOGOCOS Naturkosmetik Limpiador, exfoliante y mascarilla arcilla blanca
• botanical
• Manufaktura Carlsbad Relax Pečující krém na ruce
• plant line crema hidratantă pentru mâini
• Blistex MedPlus Lippenbalsem Stick
• Palmer’s Coconut Oil Formula
• Palmer’s Coconut Oil Formula
• ELEMIS Travel Size Pro-Collagen Cleansing Balm
• L.A. Girl Sweet lip Scrub
• dry oil with coconut oil
• Kirkland Moisture Conditioner
• marc anthony argan shampoo
• ATTITUDE Hand Cream
• Shiseido Perfect Cleansing Oil
• Shea Moisture 100% Virgin Coconut Oil Moisture Boosting Shampoo
• NEEM AURA Concentrated Neem Cream
• burt’s bees baby nourishing lotion original
• Josie Maran Argan Cleansing Oil
• fresh Travel Size Sugar Strawberry Exfoliating Face Wash
• cantu shea butter for natural hair
• SoCozy kids Curl Shampoo
• Logona Crème contour des yeux
• Caudalie PREMIER CRU LA CRÈME
• Bourjois, Ecoute ta nature ! by Yannick Noah Crème de soin nourrissante à partager
• Kéranove Naturanove
• L’Occitane, L’Occitane en Provence Crème réjouissante miel & citron
• L’Occitane au Brésil L’Occitane au Brésil Condicionador Cumaru Essência
• dove shampoo
• Durance Huile de massage aux huiles essentielles
• Vita Citral Baume Protecteur Hydratant Intense 24H