RESVERATROL

📋 Quick facts

Description: RESVERATROL — antioxidant, anti-aging.

All Functions: antioxidant, anti-aging

Quick Facts:

• Category: active

Proven Benefits At A Glance:

• Resveratrol is a polyphenol found in grape skins, berries, wine, and peanuts
• It has antioxidant, anti-inflammatory, and antimicrobial properties
• Research suggests it may support skin health, collagen production, and wound healing
• It’s generally well-tolerated but has low bioavailability when ingested
• More human studies are needed to confirm many potential benefits

⚗️ Chemical Overview

Ethinamate is a carbamate ester that is the 1-vinylcyclohexyl ester of carbamic acid. A short-acting sedative-hypnotic, it was formerly used to treat insomnia. It has a role as a sedative. It is a carbamate ester and a terminal acetylenic compound. Ethinamate is a DEA Schedule IV controlled substance. Substances in the DEA Schedule IV have a low potential for abuse relative to substances in Schedule III. It is a Depressants substance. Ethinamate is a short-acting sedative-hypnotic medication used to treat insomnia. Like many such similar medications, the regular use of ethinamate can result in the development of drug tolerance in a patient. Nevertheless, the medication itself is generally no longer effective after using it for greater than 7 days. Structurally, it does not resemble the barbituates, but it shares many effects with this class of drugs; the depressant effects of ethinamate are, however, generally milder than those of most barbiturates.

Source(s): DrugBank, ChEBI, Drug Enforcement Administration (DEA), via PubChem

📊 Comedogenicity

🛡️ Safety rating

Safety tier is a starting heuristic from regulatory status and comedogenic rating, not a dermatological verdict — see our Terms for the full disclaimer. Research confidence reflects how many real cited studies back this ingredient, not the strength of their findings.

🌍 Regulatory Status

💧 Skin Type Compatibility

⚠️ Don’t Combine With

📚 Research & Evidence

🔬 The Science

Resveratrol is a type of plant compound called a polyphenol that appears naturally in grape skins and seeds, along with berries and peanuts (Acta Biochim Pol, 2019). The compound has generated significant research interest because it exhibits multiple biological activities in laboratory and animal studies. #1: Antioxidant and anti-inflammatory effects. Resveratrol can neutralize harmful free radicals and reduce inflammatory responses in cells (Crit Rev Food Sci Nutr, 2018; Int Wound J, 2022). When applied topically to skin, it protects cells against oxidative damage from free radicals and UV radiation by reducing the expression of certain inflammatory factors called AP-1 and NF-kB (J Cosmet Laser Ther, 2019).

#2: Skin aging and collagen. Topical resveratrol formulations have shown the ability to penetrate the skin barrier and may stimulate fibroblasts—the cells that produce collagen—potentially increasing collagen III concentration (J Cosmet Laser Ther, 2019). Additionally, resveratrol can bind to estrogen receptors on skin cells, which may help stimulate production of collagen types I and II (J Cosmet Laser Ther, 2019). These effects may help slow photoaging, the premature aging caused by sun exposure (J Cosmet Laser Ther, 2019). #3: Wound healing and scarring. Preliminary research suggests resveratrol’s antioxidant, anti-inflammatory, and cell-protective effects may support wound healing and help prevent excessive scarring, though the Int Wound J, 2022 review notes that more rigorous studies are needed to confirm these effects.

Important limitations: When ingested, resveratrol has “low bioavailability and solubility,” meaning your body absorbs relatively little of it (Acta Biochim Pol, 2019). While animal studies and laboratory research show promise for resveratrol against conditions like diabetes, cardiovascular issues, and various cancers, the evidence in humans remains limited (Nat Rev Drug Discov, 2006; Acta Biochim Pol, 2019). Most research on skin benefits comes from laboratory studies and animal models rather than large human trials (Int Wound J, 2022).

📄 Related Research

Matched by search — not necessarily verified support for every statement above.

• Galiniak S et al. (2019). Health benefits of resveratrol administration. Acta Biochim Pol.
• Baur JA et al. (2006). Therapeutic potential of resveratrol: the in vivo evidence. Nat Rev Drug Discov.
• Rauf A et al. (2018). Resveratrol as an anti-cancer agent: A review. Crit Rev Food Sci Nutr.
• Ratz-Łyko A et al. (2019). Resveratrol as an active ingredient for cosmetic and dermatological applications: a review. J Cosmet Laser Ther.
• Hecker A et al. (2022). The impact of resveratrol on skin wound healing, scarring, and aging. Int Wound J.

🧴 Products Containing RESVERATROL

• MAC Studio Radiance 24HR Luminous Lift Concealer NC11
• Some By Mi Some By Mi Retinol Intense Reactivating Serum 50ml
• Sesderma Hydraderm Hyal C-Vit Hidraderm Hyal C-Vit
• Mad Hippie Daily protective serum.
• I Dew Care Namaste Kitten Clarifying Cannabis Sativa Hemp Seed Oil Cleanser
• Null premium Whitening Lotion