Description: RETINYL PALMITATE — mild vitamin A derivative, antioxidant, gentle anti-aging.
All Functions: mild vitamin A derivative, antioxidant, gentle anti-aging
Quick Facts:
- Category: active
- Regulatory Note: Restricted in the EU
Proven Benefits At A Glance:
- Retinyl palmitate is a vitamin A derivative used in skincare products for anti-aging
- Research suggests it may help protect skin from UVB damage and support collagen
- It’s been associated with skin irritation, redness, peeling, and dryness in conventional formulations
- Scientists are exploring better delivery methods to improve tolerance and effectiveness
Safety tier is a starting heuristic from regulatory status and comedogenic rating, not a dermatological verdict — see our Terms for the full disclaimer. Research confidence reflects how many real cited studies back this ingredient, not the strength of their findings.
🧪 RETINYL PALMITATE
RETINYL PALMITATE
CAS Number: 79-81-2
Also Known As: —
Category: active
EC Number: 201-228-5
Korean Name: 레티닐팔미테이트
Retinol, hexadecanoate
RETINYL PALMITATE is an active ingredient used in skincare formulations.
🌍 Regulatory Status
EU max concentration: (a) 0,05 % Retinol Equivalent (RE) (b) 0,3 % RE
EU conditions: For any cosmetic product containing Retinol, Retinyl Acetate or Retinyl Palmitate the following, labelling is obligatory: ‘Contains Vitamin A. Consider your daily intake before use’.
📊 Comedogenicity
📚 Research & Evidence
🔬 The Science
Retinyl palmitate is a form of vitamin A that your skin can absorb, store, and convert into active compounds. Here’s what current research shows:
#1: Protection from sun damage — Studies demonstrate that retinyl palmitate can reduce collagen breakdown in skin cells exposed to UVB radiation, and it may lower inflammatory markers (IL-6, IL-1β, TNF-α) triggered by sun exposure (Front Pharmacol, 2023). The mechanism appears to involve multiple cellular pathways related to inflammation, collagen production, and cell survival. #2: Support for skin repair — In laboratory studies, retinyl palmitate increased the rate at which skin cells migrate, which researchers suggest could help with damage repair and cell viability (Front Pharmacol, 2023).
When applied to human skin cells in a lab, it accelerated cell proliferation and boosted procollagen synthesis—a precursor to mature collagen—by 111% at a specific concentration (Antioxidants (Basel), 2020). #3: Cellular effects — Retinyl palmitate appears to work by influencing how skin cells divide and differentiate, processes that affect aging, immune function, and wound healing (Vitam Horm, 2007). Important limitation: The sources note that conventional topical retinyl palmitate formulations are commonly associated with adverse reactions including skin irritation, redness, excessive peeling, and dryness (Nanomaterials (Basel), 2020). Researchers are actively developing improved delivery systems to address these tolerability issues. The research base consists mainly of laboratory and cell studies; human clinical trial data in these abstracts is limited.
💧 Skin Type Compatibility
⚠️ Don’t Combine With
🧴 Products Containing RETINYL PALMITATE
- lacalut
- Aldi Lacura sensitive shower cream
- Anti-Tage Spezialcreme
- АО "Ступинский химический завод" гель для бритья men ultra one
- Corsair Toiletries 2in1 Shampoo & Conditioner Despicable Me
- Tiger Moon Retinol Night Cream
- Charlotte Tilbury magic eye
- Soraya Ideal Effect 40+ Krem wygładzająco-ujędrniający
- Poland apis
- Bioélixire Odżywka do włosów zniszczonych
- Bi-Oil Bi-Oil Körperöl, 125 ml
- Crema de masajes
- Arad Body Soufflé
- Bagovit Emulsión hidratante revitalizante, efecto luminoso
- Idraet Pro Reti-C Retinol & Vitamin C
- Carrefour Soin revitalisant anti-rides Nuit
- Bi Oil Bi oil huile de soin spécialiste
- Loreal norge as / slt Revitalift Natt 50ml Loreal
- Les Cosmetiques Facial pieles sensibles spf30 sun ultimate
- Les Cosmetiques Loción solar spf30 sun ultimate
📄 Related Research
Matched by search — not necessarily verified support for every statement above.
- Johnson W Jr (2017). Retinol and Retinyl Palmitate. Int J Toxicol.
- Shu P et al. (2023). Efficacy and mechanism of retinyl palmitate against UVB-induced skin photoaging. Front Pharmacol.
- Fu PP et al. (2007). Physiological role of retinyl palmitate in the skin. Vitam Horm.
- Choi BH et al. (2020). Microbial Production of Retinyl Palmitate and Its Application as a Cosmeceutical. Antioxidants (Basel).
- Algahtani MS et al. (2020). Nanoemulgel for Improved Topical Delivery of Retinyl Palmitate: Formulation Design and Stability Evaluation. Nanomaterials (Basel).
Similar Ingredients


📰 More News
-
The CCL20-CCR6 axis predominantly drives IL-17-mediated psoriasis while modestly contributing to papain-induced type 2 inflammation
PubMed · 23 days ago
-
SkinCeuticals Just Reformulated Its C E Ferulic Serum
Allure · 14 days ago
-
Are Sunscreen Oils Just Tanning Oils in Disguise? Experts Weigh In
Allure · 14 days ago
-
Update to RIFM fragrance ingredient safety assessment, propenylguaethol, CAS Registry Number 94-86-0
PubMed · 14 days ago
-
Earth Harbor Obscura Night Repair Concentrate Review
Allure · 13 days ago
-
Okay, We’ll Bite: Fruity Perfumes Are Cool
Allure · 13 days ago
