VINYLIDENE FLUORIDE

📋 Quick facts

Description: VINYLIDENE FLUORIDE — VINYLIDENE FLUORIDE. Formula: C2H2F2. MW: 64.03. IUPAC: 1,1-difluoroethene.

Quick Facts:

• Category: other
• Also Known As: Vinylidene fluoride, 1,1-Difluoroethylene

Proven Benefits At A Glance:

• PVDF (poly(vinylidene fluoride)) is a piezoelectric polymer used in biomedical applications including tissue repair and sensors
• PVDF and its copolymers can generate electrical signals without an external power source
• Research shows PVDF-based materials in medical scaffolds for bone, nerve, muscle, skin, and blood vessel repair
• PVDF composites have been studied for flexible sensors that monitor physiological activities and humidity
• Limited direct evidence of PVDF use in topical skincare products; sources focus on biomedical implants and wearable electronics

⚗️ Chemical Overview

1,1-Difluoroethylene (or vinylidene fluoride) is a colorless gas which is flammable in the ranges of 5.5 to 21%. It is toxic by inhalation and contact. It is slightly soluble in water and soluble in alcohol and ether. Under prolonged exposure to fire or intense heat the containers may rupture violently and rocket. Vinylidene fluoride is an organofluorine compound and an olefinic compound. structure

Source(s): Medical Subject Headings (MeSH), CAMEO Chemicals, ChEBI, via PubChem

📊 Comedogenicity

🛡️ Safety rating

Safety tier is a starting heuristic from regulatory status and comedogenic rating, not a dermatological verdict — see our Terms for the full disclaimer. Research confidence reflects how many real cited studies back this ingredient, not the strength of their findings.

🌍 Regulatory Status

💧 Skin Type Compatibility

⚠️ Don’t Combine With

📚 Research & Evidence

🔬 The Science

The research on PVDF is primarily focused on biomedical engineering and flexible electronics rather than cosmetic skincare. Here’s what the science actually shows:

#1: Piezoelectric properties — PVDF and its copolymers (such as poly(vinylidene fluoride-co-trifluoroethylene)) are piezoelectric materials, meaning they can generate electrical signals when mechanically stressed or deformed, without needing an external power source (ACS Biomater Sci Eng, 2024). This property is thought to mimic natural biological signals found in tissues like lungs. #2: Tissue engineering applications — In medical research, PVDF scaffolds have been investigated for guiding tissue repair in bone, nerve, muscle, skin, and blood vessel applications by providing a biochemical environment for cell growth and adhesion (ACS Biomater Sci Eng, 2024).

One study specifically examined PVDF copolymers combined with zinc oxide for lung tissue engineering, finding anti-inflammatory effects and antimicrobial properties in laboratory conditions (Tissue Eng Part A, 2020). #3: Sensor and wearable technology — PVDF has been used as a matrix material in flexible sensors for monitoring physiological activities. Research describes PVDF-based piezoresistive sensors for detecting pressure and movement, and PVDF membranes for humidity sensing in wearable applications (ACS Appl Mater Interfaces, 2022; J Colloid Interface Sci, 2022). Important limitation: None of these sources describe PVDF being used in topical skincare products or applied directly to skin for cosmetic purposes.

The research concentrates on implanted medical devices, tissue scaffolds, and wearable electronics. Claims about PVDF benefits for skin health, wrinkles, hydration, or other cosmetic concerns are not supported by these abstracts.

📄 Related Research

Matched by search — not necessarily verified support for every statement above.

• Sun W et al. (2024). Scaffold-Based Poly(Vinylidene Fluoride) and Its Copolymers: Materials, Fabrication Methods, Applications, and Perspectives. ACS Biomater Sci Eng.
• Guo W et al. (2021). Fabrication of Poly(Vinylidene Fluoride)/Graphene Nano-Composite Micro-Parts with Increased β-Phase and Enhanced Toughness via Micro-Injection Molding. Polymers (Basel).
• Azimi B et al. (2020). Electrospun ZnO/Poly(Vinylidene Fluoride-Trifluoroethylene) Scaffolds for Lung Tissue Engineering. Tissue Eng Part A.
• Jing M et al. (2022). Porous AgNWs/Poly(vinylidene fluoride) Composite-Based Flexible Piezoresistive Sensor with High Sensitivity and Wide Pressure Ranges. ACS Appl Mater Interfaces.
• Zhao H et al. (2022). Single-sided and integrated polyaniline/ poly(vinylidene fluoride) flexible membrane with micro/nanostructures as breathable, nontoxic and fast response wearable humidity sensor. J Colloid Interface Sci.

🧴 Products Containing VINYLIDENE FLUORIDE