ACETAMINOSALOL

Description: ACETAMINOSALOL — ANTIMICROBIAL, UV ABSORBER.

All Functions: ANTIMICROBIAL, UV ABSORBER

Quick Facts:

• Category: preservative

Proven Benefits At A Glance:

• Acetaminosalol is a compound that researchers have studied as a potential tool for targeting ulcerative colitis (an inflammatory bowel condition)
• In research, acetaminosalol was attached to a radioactive tracer (technetium-99m) to help visualize it in the body
• The compound showed an ability to bind to PPAR-gamma receptors, which are involved in inflammatory responses
• When formulated into tiny microspheres (small particles), acetaminosalol accumulated preferentially in the colon in animal studies

Safety tier is a starting heuristic from regulatory status and comedogenic rating, not a dermatological verdict — see our Terms for the full disclaimer. Research confidence reflects how many real cited studies back this ingredient, not the strength of their findings.

🧪 ACETAMINOSALOL

ACETAMINOSALOL

CAS Number: 118-57-0

Also Known As: —

Category: preservative

EC Number: 204-261-3

Korean Name: 아세타미노살롤

4′-Hydroxyacetanilide salicylate; Benzoic acid, 2-hydroxy-, 4-(acetylamino)phenyl ester

ACETAMINOSALOL is a preservative ingredient used in skincare formulations.

🌍 Regulatory Status

📊 Comedogenicity

📚 Research & Evidence

🔬 The Science

Acetaminosalol has been investigated primarily as a diagnostic and therapeutic agent rather than a cosmetic skincare ingredient. The available research focuses on its potential medical application in ulcerative colitis, an inflammatory bowel disease. #1: Researchers labeled acetaminosalol with technetium-99m (a radioactive isotope) to track where it travels in the body. The labeling process achieved a 98.9% yield, meaning nearly all of the acetaminosalol was successfully tagged with the radioactive marker (J Labelled Comp Radiopharm, 2024). #2: The compound shows affinity for PPAR-gamma receptors—cellular structures involved in regulating inflammation—based on computer modeling studies (J Labelled Comp Radiopharm, 2024). #3: In animal studies with ulcerative colitis, acetaminosalol microspheres (particles with a mean size of about 201 micrometers) accumulated in the colon at levels of 56.5% within 4 hours, suggesting the formulation could preferentially deliver the compound to inflamed tissue (J Labelled Comp Radiopharm, 2024).

Importantly, the single available abstract addresses only medical research in animals, not skincare efficacy or safety in human skin applications. No data currently supports its use as a consumer skincare ingredient.

💧 Skin Type Compatibility

⚠️ Don’t Combine With

🧴 Products Containing ACETAMINOSALOL

📄 Related Research

Matched by search — not necessarily verified support for every statement above.

• El-Kawy OA et al. (2024). Preparation and evaluation of radiolabeled acetaminosalol microspheres: A new potential selective radiotracer for ulcerative colitis early diagnosis. J Labelled Comp Radiopharm.