MYRISTYL MYRISTATE

📋 Quick facts

Description: MYRISTYL MYRISTATE — emollient, thickener.

All Functions: emollient, thickener

Quick Facts:

• Category: emollient

Proven Benefits At A Glance:

• Myristyl myristate is a lipid used in nanostructured lipid carriers (NLCs)—tiny particles designed to deliver active ingredients
• It forms stable, spherical nanoparticles roughly 90–200 nanometers in size
• Research has explored its use in formulations for sunscreen, anti-parasitic drugs, and plant-based actives
• Nanoparticles made with myristyl myristate show good stability over months of storage
• Cell safety testing in research showed these formulations had low toxicity profiles

⚗️ Chemical Overview

Tetradecyl tetradecanoate is a tetradecanoate ester (myristate ester) resulting from the formal condensation of the carboxy group of tetradecanoic acid (myristic acid) with the hydroxy group of tetradecan-1-ol (myristyl alcohol). Used as an emollient. It has a role as an algal metabolite. It is a wax ester and a tetradecanoate ester. It is functionally related to a tetradecan-1-ol.

Source(s): ChEBI, via PubChem

📊 Comedogenicity

🛡️ Safety rating

Safety tier is a starting heuristic from regulatory status and comedogenic rating, not a dermatological verdict — see our Terms for the full disclaimer. Research confidence reflects how many real cited studies back this ingredient, not the strength of their findings.

🌍 Regulatory Status

💧 Skin Type Compatibility

Derived from this ingredient’s irritancy potential and comedogenicity rating against the needs of each skin type — e.g. oily and acne-prone skin are marked down for pore-clogging ingredients, sensitive skin for irritants. A starting heuristic, not a dermatological verdict.

⚠️ Don’t Combine With

📚 Research & Evidence

🔬 The Science

Myristyl myristate is a synthetic lipid—a waxy, oil-like molecule—that acts as a structural component in nanostructured lipid carriers (NLCs). Think of NLCs as microscopic delivery vehicles: myristyl myristate forms the solid lipid core, and when combined with other lipids and surfactants (emulsifying agents), it creates stable spherical nanoparticles typically 90–200 nanometers across. #1: In research published in Pharmaceutics (2022), nanoparticles made with myristyl myristate and clay showed spherical, monodisperse structures around 200 nm with polydispersity indices under 0.3, remaining stable for 60 days, and all samples showed cell viability above 60%. #2: A 2023 study in Beilstein Journal of Nanotechnology demonstrated that myristyl myristate-based nanocarriers achieved approximately 80% encapsulation efficiency (meaning 80% of the active ingredient was successfully trapped inside), with mean particle size around 150 nm and stability maintained for at least six months; hemolytic testing (measuring damage to red blood cells) showed insignificant effects.

#3: Research in Pharmaceutics (2023) using myristyl myristate nanoparticles showed spherical morphology with 144–175 nm diameter and over 70% encapsulation efficiency, with hemotoxicity assays demonstrating safety profiles below 3.7%. #4: A 2021 Pharmaceutics study found myristyl myristate-based systems achieved average diameters around 200 nm with polydispersity indices under 0.30 and showed stability at high temperatures. #5: An AAPS PharmSciTech study (2020) produced sunscreen formulations with myristyl myristate showing average sizes of 91.5–131.7 nm, sphere-like morphology by microscopy, and demonstrated a sun protection factor around 40 in testing. The sources are limited to pharmaceutical and cosmetic research contexts; they do not provide information about myristyl myristate’s direct benefits when applied to skin outside of these nanoparticle delivery systems.

📄 Related Research

Matched by search — not necessarily verified support for every statement above.

• Barbosa RM et al. (2022). Hybrid Lipid/Clay Carrier Systems Containing Annatto Oil for Topical Formulations. Pharmaceutics.
• Muraca G et al. (2023). Nanostructured lipid carriers containing benznidazole: physicochemical, biopharmaceutical and cellular in vitro studies. Beilstein J Nanotechnol.
• Boztepe T et al. (2023). Design, Synthesis, Characterization, and Evaluation of the Anti-HT-29 Colorectal Cell Line Activity of Novel 8-Oxyquinolinate-Platinum(II)-Loaded Nanostructured Lipid Carriers Targeted with Riboflavin. Pharmaceutics.
• Ferreira MA et al. (2021). Annatto Oil Loaded Nanostructured Lipid Carriers: A Potential New Treatment for Cutaneous Leishmaniasis. Pharmaceutics.
• do Prado AH et al. (2020). Synthesis and Characterization of Nanostructured Lipid Nanocarriers for Enhanced Sun Protection Factor of Octyl p-methoxycinnamate. AAPS PharmSciTech.

🧴 Products Containing MYRISTYL MYRISTATE

• nivea nivea cream
• Eucerin Eucerin Lip Activ Soin Actif Levres Stick 4.8G (lip Care)
• Nivea Sun kids Lait protecteur Protect & Sensitive
• Nivea Baby sun Crème solaire très haute protection FPS 50+
• Nivéa Nivea soft
• Balea Beauty Effect Tagescreme
• lavera Händchenhalten Handcreme
• cien cien bb crème
• alverde Après lotion mit mir
• Null alverde
• alverde Mamaglück Körperbutter Wilde Malve
• Isana Deo Roll-On Fresh
• Elkos Fresh Deodorant
• Today Today Soft Cream Moisturizing care for face & body
• BIO, Cosmébio, Monsavon Monsavon BIO Déodorant Femme Bille Citron Touche de Verveine 50ml
• Unilever, Dove, For women Dove bille bio euca 50ml
• Unilever, Dove, For women Dove bille bio ging 50ml
• ACO Kids Active Sun Lotion SPF 50+
• bio naïa Déodorant à l’eau de coco
• Stirling Soap Co. Bergamot Lavender Post Shave Balm
• Deliplus Anti manchas
• Cosmia Crème corps réparatrice
• Alverde Cremegel Hydro
• La-roche-posay Nutritic Lèvres – soin transformation lèvres desséchées
• Unilever, Dove Dove deo bio pdp the2x50
• Unilever, Dove Dove deo bio pdp bil eucx2
• BIO, Monsavon MONSAVON BIO Déodorant Femme Bille Aloé Vera Vanille 2x50ml
• BIO, Monsavon MONSAVON BIO Déodorant Femme Bille Citron Touche de Verveine 2x50ml
• BIO, Monsavon MONSAVON BIO Déodorant Femme Bille Rose Thé Vert 2x50ml
• Schmidt’s Schmidt’s Déodorant Bille Charbon + Magnésium 50ml
• Schmidt’s, Schmidts Schmidt’s Déodorant Bille Rose + Vanille 50ml
• La Roche-Posay Effaclar Duo (+) Unifiant Teinte Light
• Palmolive antiklit
• Garnier Body superfood
• Crème nutri-eclat vitamine C
• Yves Rocher Pure calmille depuis 1964 since
• blistex lip medex
• Blistex
• Labello Hydro care
• Kiehl’s Ultra facial cream