SODIUM HYALURONATE CROSSPOLYMER

Description: SODIUM HYALURONATE CROSSPOLYMER — hydration, film-forming, longer-lasting surface hydration.

All Functions: hydration, film-forming, longer-lasting surface hydration

Quick Facts:

• Category: humectant

Proven Benefits At A Glance:

• Sodium hyaluronate crosspolymer is a modified form of hyaluronic acid designed to stay on skin longer than regular hyaluronic acid
• In a 56-day study, a cream containing this ingredient showed improvements in skin hydration, firmness, and elasticity
• The ingredient is derived from hyaluronic acid, which naturally declines with age and contributes to dryness and loss of elasticity
• Research on this ingredient is limited; only one published dermatology study specifically evaluated it in a skincare product

Safety tier is a starting heuristic from regulatory status and comedogenic rating, not a dermatological verdict — see our Terms for the full disclaimer. Research confidence reflects how many real cited studies back this ingredient, not the strength of their findings.

🧪 SODIUM HYALURONATE CROSSPOLYMER

SODIUM HYALURONATE CROSSPOLYMER

CAS Number: 105524-32-1

Also Known As: —

Category: humectant

Korean Name: 소듐하이알루로네이트크로스폴리머

Hyaluronic acid, sodium salt, polymer with 1,1′-sulfonylbis[ethene]

SODIUM HYALURONATE CROSSPOLYMER is a humectant ingredient used in skincare formulations.

🌍 Regulatory Status

📊 Comedogenicity

📚 Research & Evidence

🔬 The Science

Sodium hyaluronate crosspolymer is a chemically modified version of hyaluronic acid—a naturally occurring substance found in skin that holds moisture and supports elasticity. The “crosspolymer” structure means hyaluronic acid molecules are chemically linked together in a network, which theoretically allows the ingredient to remain on skin longer than standard hyaluronic acid (Clin Cosmet Investig Dermatol, 2017). #1: One clinical study found that after 56 days of twice-daily application in a multi-ingredient cream, skin hydration increased by 12% compared to baseline, measured with specialized equipment (Clin Cosmet Investig Dermatol, 2017). #2: The same study reported skin firmness improved by 29% and elasticity by 20% over the same period (Clin Cosmet Investig Dermatol, 2017).

#3: Users also reported visible improvements in skin texture and a reduction in brown and red spots (Clin Cosmet Investig Dermatol, 2017). However, it’s important to note that this ingredient was tested only as part of a formulation containing multiple active ingredients—carnosine, Alteromonas ferment extract, and a tripeptide—so we cannot isolate the specific contribution of the sodium hyaluronate crosspolymer alone. The scientific literature on this ingredient for skincare is currently limited to this single study, making it difficult to draw broader conclusions about its standalone efficacy.

💧 Skin Type Compatibility

⚠️ Don’t Combine With

🧴 Products Containing SODIUM HYALURONATE CROSSPOLYMER

• Labcare, Labcare cosmetics Crema viso anti-age
• RoC RoC Multi Correxion 5 in 1 Anti-Aging Eye Cream
• NIOD Multi-Molecular Hyaluronic Complex (MMHC2)
• The Ordinary Lactic Acid 10% + HA
• Drunk Elephant C-Firma™ Vitamin C Day Serum
• Drunk Elephant T.L.C. Framboos Glycolic Night Serum
• Cien Hydrating facial cleanser
• Boob tape remover
• Nacomi Serum Retinol 0,25%
• Nacomi Nacomi Krem Intens N Nawilżający
• pond’s Limpiador facial
• Dr. Ceuracle Hyal Reyouth Moist Sun SPF50+ PA++++ moisturizing UV protection face & body
• Hyggee pH Hyaluron Gel Cleanser
• NIOD Copper Amino Isolate Serum 3 1:1 (CAIS3)
• Dr. Althea Dr.Althea 147 Barrier Cream 50ml
• collagen peptide
• Laneige Water Bank Hyaluronique Bleu
• H20
• RoC RoC Derm Correxion Dual Eye Cream with Advanced Retinol

📄 Related Research

Matched by search — not necessarily verified support for every statement above.

• Conejos-Sánchez I et al. (2026). A rationally designed polypeptide-based hybrid platform for targeted intranasal brain drug delivery. Biomaterials.
• Garre A et al. (2017). Redefining face contour with a novel anti-aging cosmetic product: an open-label, prospective clinical study. Clin Cosmet Investig Dermatol.