Mia Seilern
TRIMETHYLSILOXYSILICATE
⚠️ Data is provided for informational purposes only. It may contain inaccuracies and should be independently verified. This is not medical advice. Consult a healthcare professional before making health decisions.

Description: TRIMETHYLSILOXYSILICATE — silicone, film-forming, adds water resistance.

All Functions: silicone, film-forming, adds water resistance

Quick Facts:

  • Category: emollient

Proven Benefits At A Glance:

  • A silicone-based ingredient used in cosmetics as a film-former, thickener, and skin conditioner
  • Functions as both a soft and hard film-forming agent in sunscreens and skincare products
  • Creates a persistent, non-occlusive layer on skin that resists washing
  • Deemed safe by the Cosmetic Ingredient Review Expert Panel when formulated to avoid respiratory irritation
  • Can enhance UV protection in sunscreens when combined with other film-forming agents
Safety: Generally Low ConcernResearch confidence: Good

Safety tier is a starting heuristic from regulatory status and comedogenic rating, not a dermatological verdict — see our Terms for the full disclaimer. Research confidence reflects how many real cited studies back this ingredient, not the strength of their findings.

🧪 TRIMETHYLSILOXYSILICATE

Chemical structure of TRIMETHYLSILOXYSILICATE

TRIMETHYLSILOXYSILICATE

CAS Number: 56275-01-5

Also Known As:

Category: emollient

Korean Name: 트라이메틸실록시실리케이트

Silica, reaction products with trimethylsilane

TRIMETHYLSILOXYSILICATE is an emollient ingredient used in skincare formulations.

siliconefilm-formingadds water resistance

🌍 Regulatory Status

EU: No restriction on fileUS: No restriction on file

📊 Comedogenicity

No data yet
Not rated for this ingredient yet.

📚 Research & Evidence

PUBMED CITATIONS
5
Data sources: EU CosIng PubMed

🔬 The Science

Trimethylsiloxysilicate (often abbreviated TMSS) is a modified silicone polymer that belongs to a family of ingredients called siloxysilicates. Here’s what the research shows about how it works and what it does. **What it does in formulas:** The Cosmetic Ingredient Review Expert Panel identified multiple functions for trimethylsiloxysilicate in cosmetics (Int J Toxicol, 2013). #1: It acts as an antifoaming agent, preventing unwanted bubbles. #2: It works as an anticaking agent and bulking agent, helping powders flow smoothly. #3: It conditions skin as an emollient (softening) and occlusive (moisture-barrier) agent. #4: It modifies slip—the glide and feel of a product on skin.

#5: It increases viscosity in non-aqueous (oil-based) formulations, making products thicker. **Film-forming and durability:** One of trimethylsiloxysilicate’s most notable properties is its ability to form a durable film on skin. In a 2021 study on essential oil delivery (Int J Pharm, 2021), researchers used a 100% trimethylsiloxysilicate resin specifically because it creates “a very substantive and non-occlusive film”—meaning it sticks around on skin without blocking it from breathing. A 1988 analysis (Int J Cosmet Sci, 1988) found that when combined with other silicones, trimethylsiloxysilicate improves “substantivity,” the ability of a product to stay on skin through multiple wash cycles. The resin’s low solubility is what drives this persistence.

**Use in sunscreens:** Recent research (Polymers (Basel), 2024) explored trimethylsiloxysilicate as a “hard film” component in multi-layer sunscreen formulations. When combined with other film-forming agents and powder ingredients with similar chemical structures, it enhanced UV protection measurably: sun protection factor (SPF) increased by 61.58% and UVA protection factor (PFA) increased by 43.84% in the tested formula. The ingredient’s interaction with other components helped prevent clumping and created a more uniform protective layer. **Safety:** The Cosmetic Ingredient Review Expert Panel (Int J Toxicol, 2013) concluded that trimethylsiloxysilicate is safe as used in cosmetics, provided the final product is formulated to avoid irritating or sensitizing the respiratory tract—a consideration for powder formulations or spray products.

**Limitations in available research:** The sources provided focus mainly on technical functionality and safety assessment. There is limited consumer-facing clinical data on specific skin benefits like anti-aging, acne treatment, or visible texture improvement. Most studies examine trimethylsiloxysilicate within complex multi-ingredient formulations, making it difficult to isolate its individual contribution to skin appearance or feel.

💧 Skin Type Compatibility

No data yet
Per-skin-type data isn’t curated for this ingredient yet.

⚠️ Don’t Combine With

No data yet
No known incompatibilities on file for this ingredient.

🧴 Products Containing TRIMETHYLSILOXYSILICATE

📄 Related Research

Matched by search — not necessarily verified support for every statement above.

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