ACETYL CEDRENE

📋 Quick facts

Description: ACETYL CEDRENE — FRAGRANCE.

All Functions: FRAGRANCE

Quick Facts:

• Category: other
• Regulatory Note: Restricted in the EU

Proven Benefits At A Glance:

• Acetyl cedrene is a fragrance ingredient belonging to a chemical class called Alkyl Cyclic Ketones
• It has been evaluated for multiple safety endpoints including skin irritation, eye irritation, and skin sensitization
• At high doses in animal studies, it caused reduced food consumption and body weight gain in pregnant rats, but did not cause birth defects
• Rare cases of allergic contact dermatitis from acetyl cedrene in cosmetics have been documented
• Environmental research shows it can be broken down by aquatic organisms

📊 Comedogenicity

🛡️ Safety rating

Safety tier is a starting heuristic from regulatory status and comedogenic rating, not a dermatological verdict — see our Terms for the full disclaimer. Research confidence reflects how many real cited studies back this ingredient, not the strength of their findings.

🌍 Regulatory Status

💧 Skin Type Compatibility

⚠️ Don’t Combine With

📚 Research & Evidence

🔬 The Science

Acetyl cedrene is a fragrance molecule classified as an Alkyl Cyclic Ketone—a structural group with a ketone functional group (a specific carbon-oxygen bond configuration) attached to cyclic hydrocarbon structures (Food Chem Toxicol, 2013). The ingredient has undergone toxicological and dermatological evaluation across multiple safety categories. #1: Developmental safety—When pregnant rats were given acetyl cedrene at doses up to 100 mg/kg/day during pregnancy, no birth defects or malformations occurred in the fetuses (Int J Toxicol, 2006). At the highest dose tested (100 mg/kg/day), pregnant animals showed reduced food intake and body weight gain during early pregnancy, but compensated by eating more later, and maternal body weights returned to normal.

The researchers established a “no-observable-adverse-effect level” (a dose threshold below which no harmful effects were detected) of 50 mg/kg/day for maternal effects and 100 mg/kg/day for fetal development (Int J Toxicol, 2006). #2: Skin sensitization—A case report documented one instance of allergic contact dermatitis (a delayed immune reaction causing rash) from acetyl cedrene in a deodorant product (Contact Dermatitis, 1994). This indicates that while sensitization appears rare, it is possible in susceptible individuals. The broader safety assessment of acetyl cedrene as a fragrance ingredient reviewed available skin irritation, eye irritation, and skin sensitization data, though the specific findings from those individual studies are not detailed in the abstracts provided (Food Chem Toxicol, 2013).

#3: Environmental behavior—When acetyl cedrene was exposed to aquatic worms in sediment, the worms survived well and could effectively break down the ingredient through biotransformation, reducing sediment concentrations by 88–99% over 14 days (Environ Toxicol Chem, 2012). This suggests the ingredient is not persistently toxic in aquatic environments and can be metabolized by organisms.

📄 Related Research

Matched by search — not necessarily verified support for every statement above.

• Scognamiglio J et al. (2013). Fragrance material review on acetyl cedrene. Food Chem Toxicol.
• Lapczynski A et al. (2006). Evaluation of the developmental toxicity of acetyl cedrene. Int J Toxicol.
• Dai L et al. (2012). Fate and effects of acetyl cedrene in sediments inhabited by different densities of the deposit feeder, Capitella teleta. Environ Toxicol Chem.
• Handley J et al. (1994). Allergic contact dermatitis from the synthetic fragrances Lyral and acetyl cedrene in separate underarm deodorant preparations. Contact Dermatitis.

🧴 Products Containing ACETYL CEDRENE

• Nivéa Nivea soft
• Seba Med Seifenfreies Waschstück
• Mitchum Women Mitchum 48h Powder Fresh Deodorant
• Laab MEN Multi-Booster Ultralekki krem nawilżająco-kojący
• BYPHASSE DEODORANT 48 H
• 4TEENS Balancing Foam Cleanser
• Lynx Africa Deodorant & Bodyspray
• cien Leche corporal almendras
• Cosmia Déodorant
• Borotalco Bagnodoccia rigenerante
• Seinz Powerwax
• Nivea Men NIVEA Men Protect & Care Antitranspirant Roller
• Dove Dove men care stick clean comfort 50 m
• Dove,Unilever Dove Men + Care Sensitive 3in1 Pflegedusche
• dusch das Duschgel Noire
• WIDIAN Melogold
• AXE Blue lavender
• Nivea Nivea body milk
• Unilever, Sure Antiperspirant Sure Sensitive for Men
• Balea MEN FRESH AFTER SHAVE