METHIONINE

📋 Quick facts

Description: METHIONINE — amino acid, part of the skin natural moisturizing factor (NMF), antioxidant support.

All Functions: amino acid, part of the skin natural moisturizing factor (NMF), antioxidant support

Quick Facts:

• Category: humectant

Proven Benefits At A Glance:

• Methionine is an essential amino acid used in food, feed, cosmetics, and pharmaceuticals
• Most methionine is currently produced through chemical synthesis rather than natural fermentation
• Methionine metabolites are involved in wound healing and metabolic processes
• Zinc methionine may offer better absorption than other forms of zinc

⚗️ Chemical Overview

Methionine is a sulfur-containing amino acid that is butyric acid bearing an amino substituent at position 2 and a methylthio substituent at position 4. It has a role as a Saccharomyces cerevisiae metabolite, a plant metabolite, an Escherichia coli metabolite, a Daphnia magna metabolite and an algal metabolite. It is a sulfur-containing amino acid and an alpha-amino acid. It is functionally related to a butyric acid. It is a conjugate base of a methioninium. It is a conjugate acid of a methioninate. It is a tautomer of a methionine zwitterion. A preparation of methionine that includes a mixture of D-methionine and L-methionine isomers. DL-methionine has been reported in Arabidopsis thaliana, Homo sapiens, and other organisms with data available.

Source(s): DrugBank, ChEBI, LOTUS – the natural products occurrence database, via PubChem

📊 Comedogenicity

🛡️ Safety rating

Safety tier is a starting heuristic from regulatory status and comedogenic rating, not a dermatological verdict — see our Terms for the full disclaimer. Research confidence reflects how many real cited studies back this ingredient, not the strength of their findings.

🌍 Regulatory Status

💧 Skin Type Compatibility

⚠️ Don’t Combine With

📚 Research & Evidence

🔬 The Science

Methionine is an essential amino acid, meaning your body cannot make it on its own and must obtain it from food or supplements (Biotechnol Adv, 2023). Currently, most methionine production relies on chemical synthesis, though researchers are exploring more sustainable microbial fermentation methods as an alternative. From a biochemistry perspective, methionine plays several interesting roles in your body. When you consume methionine, your body converts it into important molecules like S-adenosylmethionine (SAM) and S-adenosylhomocysteine (SAH), which participate in various metabolic reactions (J Intensive Care Med, 2018). Research has identified that #1: methionine salvage pathways—the biochemical “recycling” routes for methionine metabolites—show measurable changes during wound healing, particularly in deeper burn wounds treated with acellular fish skin grafts (Antioxidants (Basel), 2023).

One emerging application involves pairing methionine with zinc. Because #2: zinc methionine may have superior bioavailability compared to other zinc forms, it’s being studied as a potential dietary supplement, given zinc’s known roles in antioxidant function, immune support, and skin and connective tissue repair (Biofactors, 2006). It’s worth noting that the research on methionine’s skincare benefits specifically is limited in these sources. The wound-healing data comes from burn models and surgical contexts rather than topical skincare applications. More targeted research would be needed to establish clear consumer-facing skincare claims beyond methionine’s general roles in tissue metabolism and repair.

📄 Related Research

Matched by search — not necessarily verified support for every statement above.

• Cai M et al. (2023). Microbial production of L-methionine and its precursors using systems metabolic engineering. Biotechnol Adv.
• Kotronoulas A et al. (2023). Fish Skin Grafts Affect Adenosine and Methionine Metabolism during Burn Wound Healing. Antioxidants (Basel).
• Wexler O et al. (2018). Methionine Metabolites in Patients With Sepsis. J Intensive Care Med.
• Chien XX et al. (2006). Bioavailability, antioxidant and immune-enhancing properties of zinc methionine. Biofactors.
• Trocha K et al. (2019). Preoperative Protein or Methionine Restriction Preserves Wound Healing and Reduces Hyperglycemia. J Surg Res.

🧴 Products Containing METHIONINE

• L’Oréal, L’Oreal Luxe, Biotherm aquasource
• KIKO MILANO WHITE LOOK
• Deliplus Base 9 in 1 con vitamina alisadora
• Sally Hansen Complete Care 7-in-1 Nail Treatment
• Paul Mitchell Paul Mitchell Awapuhi Shampoo
• collagen face mask
• FILORGA TIME-FILLER Crème Absolue Correction Rides
• Filorga Filorga Hydra Filler 50ML
• OREAL PROFESSIONNEL SHAMPOOING ECLAT POUR CHEVEUX GRIS
• semilac Nail conditioner
• Herbal time хининов мицеларен шампоан
• ipca Keraglo Men