SIMMONDSIA CHINENSIS SEED OIL

Description: SIMMONDSIA CHINENSIS SEED OIL — moisturizing, closely mimics skin’s natural sebum (Jojoba Oil).

All Functions: moisturizing, closely mimics skin’s natural sebum (Jojoba Oil)

Quick Facts:

• Category: emollient
• Comedogenic Rating: 2/5

Proven Benefits At A Glance:

• Simmondsia chinensis seed oil is also called jojoba oil
• In lab studies on nasal cells, the oil showed dose-dependent effects on cell viability
• Jojoba oil can be used as a base ingredient in oleogel formulations for skin care
• One study suggests potential applications in certain ear, nose, and throat conditions, but human safety and effectiveness still need testing
• The oil has been explored as a vehicle for delivering skincare products to dry skin

Safety tier is a starting heuristic from regulatory status and comedogenic rating, not a dermatological verdict — see our Terms for the full disclaimer. Research confidence reflects how many real cited studies back this ingredient, not the strength of their findings.

🧪 SIMMONDSIA CHINENSIS SEED OIL

SIMMONDSIA CHINENSIS SEED OIL

CAS Number: 90045-98-0

Also Known As: —

Category: emollient

EC Number: 289-964-3

Simmondsia Chinensis Seed Oil is the fixed oil expressed or extracted from seeds of the desert shrub, Jojoba, Simmondsia chinensis, Buxaceae

SIMMONDSIA CHINENSIS SEED OIL is an emollient ingredient used in skincare formulations.

🌍 Regulatory Status

📊 Comedogenicity

2/5

📚 Research & Evidence

🔬 The Science

Simmondsia chinensis seed oil, commonly known as jojoba oil, has been the subject of recent research exploring its potential skincare applications, though the evidence base remains limited. #1: Cell effects in lab conditions — When researchers from J Craniofac Surg (2026) exposed nasal epithelial cells (the cells lining the nasal cavity) directly to Simmondsia chinensis seed oil in a laboratory setting, they found that the oil reduced cell viability in a dose-dependent manner, meaning higher concentrations caused stronger effects. The study used an MTT assay, a standard lab test that measures how actively cells are metabolizing, as a proxy for cell health.

At the lowest concentration tested (1 microliter), effects were already measurable, and viability declined steadily as oil concentration increased. Researchers emphasize, however, that these results are from direct cell exposure in a petri dish and that “more clinical and experimental studies are needed to determine its therapeutic potential and safety profile before it may be used in clinical practice.”

#2: Formulation vehicle — Research in Pharmazie (2013) describes jojoba oil as a base ingredient in oleogels, which are gel-like formulations designed for skincare and drug delivery. In this application, Simmondsia chinensis seed oil served as the oil phase of a formulation intended for “skin care for very dry skin.” The oleogel was noted for its “high physical, chemical, and mechanical stability,” suggesting it holds its texture and consistency well over time.

Importantly, the J Craniofac Surg study’s findings about cell inhibition were discussed as potentially relevant to certain ear, nose, and throat conditions, but the authors explicitly state that clinical safety and effectiveness have not been established. Consumer skincare applications differ fundamentally from direct cellular exposure, and neither source provides evidence about how the oil performs on intact skin in real-world use.

💧 Skin Type Compatibility

Derived from this ingredient’s irritancy potential and comedogenicity rating against the needs of each skin type — e.g. oily and acne-prone skin are marked down for pore-clogging ingredients, sensitive skin for irritants. A starting heuristic, not a dermatological verdict.

⚠️ Don’t Combine With

🧴 Products Containing SIMMONDSIA CHINENSIS SEED OIL

• Beierdorf, Nivea Naturally good crema giorno idratante
• Eucerin Eucerin Lip Activ Soin Actif Levres Stick 4.8G (lip Care)
• Nivea Intimate gel de toilette intime Douceur Huile de jojoba bio, Extrait de camomille & Acide lactique
• nivea nivea cream
• Brynild AS Labello Peach Shine 1 stk
• Beierdorf labello med repair
• labello All-Wetter set
• Nivea, Nivea Sun Sensitive Immediate Protect+, SPF30
• BRYNILD GRUPPEN AS Nivea Day Care Naturally Good 50ml
• nivea natural balance tagespflege
• Nivea Natturally good anti-age
• alverde Naturkosmetik Repair Spülung strapaziertes & brüchiges Haar
• Henkel, Schauma Sports Power-Shampoo
• Dr. Hauschka Déodorant rose
• Balea Lip palm Rosé
• Calypso facial protection
• Henkel, Schwarzkopf Shampoo – 7 Herbs – 7 Kruiden
• Nacomï White Black Face Mask
• Swiss Toniq Geneva Double Stem Cell Repair 11-in-1 Serum With Essential Oil
• Swiss Toniq Geneva Cellular Sun Defence Face & Body Sunscreen 30SPF

📄 Related Research

Matched by search — not necessarily verified support for every statement above.

• Sünnetçi G et al. (2026). A Translational Cell-Culture Study of Jojoba Oil: Potential Uses and Safety Considerations for Nasal Applications. J Craniofac Surg.
• Grysko M et al. (2013). Evaluation of the mechanism of gelation of an oleogel based on a triterpene extract from the outer bark of birch. Pharmazie.