5-BROMO-5-NITRO-1,3-DIOXANE - Skin Care Ingredients Curated By Mia Seilern

⚠️ Data is provided for informational purposes only. It may contain inaccuracies and should be independently verified. This is not medical advice. Consult a healthcare professional before making health decisions.

Description: 5-BROMO-5-NITRO-1,3-DIOXANE — PRESERVATIVE.

All Functions: PRESERVATIVE

Quick Facts:

Category: preservative

Proven Benefits At A Glance:

5-Bromo-5-nitro-1,3-dioxane (bronidox) is a bromine-containing preservative used in rinse-off cosmetics like shampoos and body cleansers
It is subject to restrictions under European cosmetic regulations
The European maximum authorized concentration is 0.1%
It is detected using specialized analytical chemistry methods

Safety: Generally Low ConcernResearch confidence: Fair

Safety tier is a starting heuristic from regulatory status and comedogenic rating, not a dermatological verdict — see our Terms for the full disclaimer. Research confidence reflects how many real cited studies back this ingredient, not the strength of their findings.

🧪 5-BROMO-5-NITRO-1,3-DIOXANE

5-BROMO-5-NITRO-1,3-DIOXANE

CAS Number: 30007-47-7

Also Known As: —

Category: preservative

EC Number: 250-001-7

Korean Name: 5-브로모-5-나이트로-1,3-디옥산

5-bromo-5-nitro-1,3-dioxane

5-BROMO-5-NITRO-1,3-DIOXANE is a preservative ingredient used in skincare formulations.

PRESERVATIVE

🌍 Regulatory Status

EU: No restriction on fileUS: No restriction on file

EU max concentration: 0.1%

📊 Comedogenicity

No data yet

Not rated for this ingredient yet.

📚 Research & Evidence

PUBMED CITATIONS

Data sources: EU CosIng PubMed

🔬 The Science

5-Bromo-5-nitro-1,3-dioxane, commonly called bronidox, is a preservative compound containing bromine that manufacturers add to rinse-off cosmetic products—meaning products you wash away rather than leave on skin, such as shampoos, body cleansers, and facial exfoliants (J Chromatogr A, 2010). #1: The European Union limits the maximum concentration allowed in cosmetics to 0.1% (J Chromatogr A, 2010). Because bronidox is subject to regulatory restrictions, cosmetic manufacturers and quality control labs need reliable methods to measure whether products actually contain the amounts they claim. #2: Analytical chemists have developed and validated testing procedures to detect bronidox in cosmetic formulations, using techniques like solid-phase microextraction paired with gas chromatography (J Chromatogr A, 2010).

These scientific methods can detect the preservative at levels well below the regulatory maximum, and researchers have confirmed the presence or absence of bronidox in commercially available cosmetic products (J Chromatogr A, 2010). The available research focuses on detection and regulation rather than skincare benefits or safety profiles for consumers.