Mia Seilern
⚠️ Data is provided for informational purposes only. It may contain inaccuracies and should be independently verified. This is not medical advice. Consult a healthcare professional before making health decisions.

Description: OENOTHERA BIENNIS OIL — rich in GLA, barrier support, anti-inflammatory (Evening Primrose Oil).

All Functions: rich in GLA, barrier support, anti-inflammatory (Evening Primrose Oil)

Quick Facts:

  • Category: emollient
  • Comedogenic Rating: 1/5

Proven Benefits At A Glance:

  • Oenothera biennis oil (evening primrose oil) contains omega-6 fatty acids, primarily linoleic acid (60-80%) and gamma-linoleic acid (8-14%)
  • Research has explored its use for women’s health concerns including PMS and breast pain, though results require consistent use over 4-6 months
  • The oil contains fluorescent compounds and other bioactive ingredients beyond just fatty acids
  • It has been studied in nanoparticle formulations for potential delivery applications
  • One small study in older men showed the oil can alter fatty acid patterns in blood
Safety: Generally Low ConcernResearch confidence: Good

Safety tier is a starting heuristic from regulatory status and comedogenic rating, not a dermatological verdict — see our Terms for the full disclaimer. Research confidence reflects how many real cited studies back this ingredient, not the strength of their findings.

🧪 OENOTHERA BIENNIS OIL

Chemical structure of OENOTHERA BIENNIS OIL

OENOTHERA BIENNIS OIL

CAS Number: 90028-66-3

Also Known As:

Category: emollient

EC Number: 289-859-2

Oenothera Biennis Oil is the fixed oil derived from the seeds of the Evening Primrose, Oenothera biennis, Onagraceae

OENOTHERA BIENNIS OIL is an emollient ingredient used in skincare formulations.

rich in GLAbarrier supportanti-inflammatory (Evening Primrose Oil)

🌍 Regulatory Status

EU: No restriction on fileUS: No restriction on file

📊 Comedogenicity

🟥⬜⬜⬜⬜

1/5

📚 Research & Evidence

PUBMED CITATIONS
5
Data sources: EU CosIng PubMed

🔬 The Science

Oenothera biennis oil, commonly called evening primrose oil or EPO, is a fixed oil that serves as a source of essential fatty acids—compounds your body needs but cannot make on its own. The oil’s composition is dominated by two types of omega-6 fatty acids: linoleic acid makes up the bulk at 60-80% of the oil, while gamma-linoleic acid comprises 8-14% (J Menopausal Med, 2019). From a skincare and wellness perspective, the research highlights several areas of investigation: #1: Studies have examined evening primrose oil’s potential benefits for women’s health issues, with the most research focused on mastalgia (breast pain) and premenstrual syndrome (PMS), though the source notes that other conditions including hot flashes have also been studied (J Menopausal Med, 2019).

Importantly, the research emphasizes that benefits are not immediate—consistent use over 4 to 6 months appears necessary (J Menopausal Med, 2019). #2: Beyond its fatty acid content, the oil contains bioactive compounds including tocopherols (a form of vitamin E) and other ingredients that research suggests may provide anti-inflammatory and antioxidant properties, similar to other plant oils studied for these effects (Molecules, 2020). One analysis used spectrofluorometric techniques to detect and compare fluorescent components in evening primrose oil alongside other botanical oils, revealing distinct chemical profiles (Molecules, 2020). #3: At the cellular level, a small study of 33 healthy men (average age 72) who consumed 2.4 grams of the oil over five weeks showed that the oil altered circulating fatty acid patterns in those with elevated platelet aggregation, though no changes were observed in those with normal baseline patterns (Ann Nutr Aliment, 1980).

This suggests the oil’s effects may depend on individual biochemical differences. The sources are limited in scope for skincare applications specifically—most research focuses on internal consumption for women’s health rather than topical use. Source 2 and Source 3 examine evening primrose oil as an industrial material and in nanoparticle form for delivery, but do not address skin benefits directly.

💧 Skin Type Compatibility

74%
Sensitive
40%
Oily
84%
Dry
84%
Combination
40%
Acne-prone
86%
Normal

Derived from this ingredient’s irritancy potential and comedogenicity rating against the needs of each skin type — e.g. oily and acne-prone skin are marked down for pore-clogging ingredients, sensitive skin for irritants. A starting heuristic, not a dermatological verdict.

⚠️ Don’t Combine With

No data yet
No known incompatibilities on file for this ingredient.

🧴 Products Containing OENOTHERA BIENNIS OIL

📄 Related Research

Matched by search — not necessarily verified support for every statement above.

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