TYROSINE

📋 Quick facts

Description: TYROSINE — amino acid, precursor to melanin production.

All Functions: amino acid, precursor to melanin production

Quick Facts:

• Category: active

Proven Benefits At A Glance:

• Tyrosine is an amino acid that serves as the starting point for melanin production in skin cells
• The sources provided focus on tyrosine kinase inhibitors (cancer and allergy medications) rather than tyrosine as a skincare ingredient
• No direct evidence supports tyrosine as a beneficial skincare ingredient in these sources
• The sources discuss side effects of tyrosine kinase drugs, not benefits of tyrosine itself

⚗️ Chemical Overview

Tyrosine is an alpha-amino acid that is phenylalanine bearing a hydroxy substituent at position 4 on the phenyl ring. It has a role as a Daphnia magna metabolite. It is a polar amino acid, an alpha-amino acid and an aromatic amino acid. It contains a 4-hydroxybenzyl group. It is functionally related to a propionic acid. It is a conjugate base of a tyrosinium. It is a conjugate acid of a tyrosinate(1-). DL-tyrosine has been reported in Allium, Daphnia magna, and Caenorhabditis elegans with data available. See also: Poly-L-tyrosine (annotation moved to); L-Tyrosine (annotation moved to).

Source(s): LOTUS – the natural products occurrence database, ChEBI, PubChem, via PubChem

📊 Comedogenicity

🛡️ Safety rating

Safety tier is a starting heuristic from regulatory status and comedogenic rating, not a dermatological verdict — see our Terms for the full disclaimer. Research confidence reflects how many real cited studies back this ingredient, not the strength of their findings.

🌍 Regulatory Status

💧 Skin Type Compatibility

⚠️ Don’t Combine With

📚 Research & Evidence

🔬 The Science

The research abstracts provided do not contain information about tyrosine as a skincare ingredient. Instead, they examine tyrosine kinase inhibitors—pharmaceutical drugs that block tyrosine kinase proteins to treat cancer and allergic conditions. However, one source does explain tyrosine’s natural role in skin biology: Tyrosine is an amino acid that begins the melanin biosynthesis process (Postepy Hig Med Dosw (Online), 2016). When ultraviolet radiation or certain endogenous agents activate melanocytes (the pigment-producing cells in skin’s basal layer), tyrosine is converted into an intermediate compound called DOPAquinone, which then undergoes a series of transformations to eventually become either eumelanin (brown-black pigment) or pheomelanin (yellow-reddish pigment).

This process is regulated by multiple intracellular signaling pathways and is influenced by pH and temperature. The remaining sources examine tyrosine kinase inhibitor medications—compounds designed to block tyrosine kinase enzymes—which are used to treat cancers and allergic diseases. These sources document the side effects of these drugs on skin, including bruising, rashes, and infections, but do not evaluate tyrosine supplementation or topical tyrosine as a skincare benefit. Without research specifically testing tyrosine as a skincare ingredient, these sources cannot support claims about its efficacy in skincare products.

📄 Related Research

Matched by search — not necessarily verified support for every statement above.

• Sibaud V et al. (2020). Dermatological Toxicities of Bruton’s Tyrosine Kinase Inhibitors. Am J Clin Dermatol.
• Shyam Sunder S et al. (2023). Adverse effects of tyrosine kinase inhibitors in cancer therapy: pathophysiology, mechanisms and clinical management. Signal Transduct Target Ther.
• Rzepka Z et al. (2016). From tyrosine to melanin: Signaling pathways and factors regulating melanogenesis. Postepy Hig Med Dosw (Online).
• Lin EV et al. (2025). Current and future landscape of Bruton tyrosine kinase inhibitors in allergy. J Allergy Clin Immunol.
• Kozuki T (2016). Skin problems and EGFR-tyrosine kinase inhibitor. Jpn J Clin Oncol.

🧴 Products Containing TYROSINE

• Babaria Aceite protector monoi
• nautilus
• beaches and creme black
• somewhere on a beach
• Paul Mitchell Paul Mitchell Awapuhi Shampoo
• collagen face mask
• FILORGA TIME-FILLER Crème Absolue Correction Rides
• Filorga Filorga Hydra Filler 50ML
• Bioderma Photoderm Bronz SPF 50+
• Bioderma Photoderm bronz spf 50+
• Atomy Atomy absolute BB no.23 spf 50
• Laboratoires Gilbert Cosmétiques Hein Poa Soins Solaires 50 spf
• averac caviar
• Roman restore conditioner
• mermaid majesty
• Bio soleil Huile sèche au réa, bonzage intense, 50% monoï de tahiti. SPF0