DIPEPTIDE DIAMINOBUTYROYL BENZYLAMIDE DIACETATE

📋 Quick facts

Description: DIPEPTIDE DIAMINOBUTYROYL BENZYLAMIDE DIACETATE — peptide, reduces appearance of expression lines (known as SYN-AKE).

All Functions: peptide, reduces appearance of expression lines (known as SYN-AKE)

Quick Facts:

• Category: active

Proven Benefits At A Glance:

• DIPEPTIDE DIAMINOBUTYROYL BENZYLAMIDE DIACETATE is one ingredient in a multi-ingredient anti-aging serum studied in recent research
• The serum containing this ingredient showed improvements in both static wrinkles (visible at rest) and dynamic wrinkles (expression lines)
• Lab studies found the serum increased elastic fibers and collagen in skin samples
• Improvements were observed in skin smoothness, radiance, pore appearance, elasticity, and firmness
• Results were statistically significant in clinical trials with 50 and 42 participants

📊 Comedogenicity

🛡️ Safety rating

Safety tier is a starting heuristic from regulatory status and comedogenic rating, not a dermatological verdict — see our Terms for the full disclaimer. Research confidence reflects how many real cited studies back this ingredient, not the strength of their findings.

🌍 Regulatory Status

💧 Skin Type Compatibility

⚠️ Don’t Combine With

📚 Research & Evidence

🔬 The Science

DIPEPTIDE DIAMINOBUTYROYL BENZYLAMIDE DIACETATE is a peptide—a short chain of amino acids, the building blocks of proteins. In research published in the *International Journal of Cosmetic Science* (2026), this ingredient was studied as part of a serum formula also containing acetyl hexapeptide-8, gluconolactone, niacinamide, and laminaria extract. Because it was tested in a multi-ingredient formula, the research doesn’t isolate this single ingredient’s effects, so we’re seeing the combined impact of all components. #1: In laboratory studies on human skin samples, the serum increased levels of elastic fibers and collagen types I, III, IV, and XVII—structural proteins that support skin firmness and resilience (*Int J Cosmet Sci*, 2026).

The serum also reduced markers of matrix metalloproteinase-1, an enzyme linked to collagen breakdown. #2: In a clinical trial with 50 participants, static wrinkles (permanent creases visible even at rest) improved significantly within the first week, with clinical scoring improving from 35% to 69% after 12 weeks of daily use (*Int J Cosmet Sci*, 2026). #3: In a second clinical trial with 42 participants, dynamic wrinkles (expression lines that appear when you move your face) showed 10–13% improvement (*Int J Cosmet Sci*, 2026). #4: Beyond wrinkles, the formula showed measurable improvements in overall skin quality: smoothness increased by 30%, radiance by 27%, pore appearance by 43%, elasticity by 33%, and firmness by 36% (*Int J Cosmet Sci*, 2026).

All improvements were statistically significant. The research is limited to one study with this specific formulation; we cannot extrapolate benefits of this ingredient in isolation or in other products.

📄 Related Research

Matched by search — not necessarily verified support for every statement above.

• Zhu M et al. (2026). The effect of a serum containing acetyl hexapeptide-8, dipeptide diaminobutyroyl benzylamide diacetate and gluconolactone on skin biomarkers, wrinkles and skin texture: Ex vivo and clinical studies. Int J Cosmet Sci.

🧴 Products Containing DIPEPTIDE DIAMINOBUTYROYL BENZYLAMIDE DIACETATE

• sophora japonica day cream
• Laab MEN Multi-Booster Ultralekki krem nawilżająco-kojący
• RoC RoC Multi Correxion 5 in 1 Anti-Aging Eye Cream
• Organic & Botanic Mandarin Orange Enhacing Day Moisturiser
• L’Oréal Revitalift filler
• L’OREAL NORGE AS L’Oreal Revitalift Filler Eye Cream 30ml
• sophora japonica night cream
• Miya Cosmetics Żel-serum pod oczy
• RoC RoC Derm Correxion Dual Eye Cream with Advanced Retinol